The National Institute for Nuclear Physics is dedicating to the unknown, the theme of this year's event, a conference/show in which scientists and artists will create a narration of physics with words, suggestions and artistic performances. It proposes to the audience an installation that traces 60 years of history and Italian research excellence in particle physics. The great mysteries of particle physics will be the stars of the conference/show called "Quello che non so" (What I Do Not Know). Dark matter, juggling and sand paintings in jazz that the National Institute for Nuclear Physics (INFN) will bring to the stage on Friday, 23 January at the Parco della Musica Auditorium in Rome, during the tenth edition of the Rome Science Festival dedicated this year to The Unknown. From the stage physicists Fernando Ferroni (INFN President), Antonio Masiero (INFN Vice President) and Camilla Maiani (researcher at the French laboratory CEA) and, in connection from Geneva, Fabiola Gianotti (director-designate of CERN) will lead us through the most fascinating questions of contemporary physics. The discussion will focus on what we still do not know: the great challenges of physics of the twenty-first century, which with leading-edge technologies and experiments is investigating "mysteries" such as dark matter, the even more unknown dark energy and the asymmetry between matter and antimatter. And exciting and curious theories and topics such as the existence of parallel universes and the possibility of time travel will also be discussed. The scientists will share the stage with writer Stefano Benni, narrator of the evening, the artists Ivan Bert, on the trumpet, Rémi Lasvenes, juggler and mimer of the Compagnie Sans Gravité and Gabriella Compagnone, sand artist, to create a unique show of its kind dedicated to the general public. The evening will be presented by Marco Castellazzi (RAI). But that's not all. INFN, in fact, will be participating in the Rome Science Festival with the Meet LHC installation. 60 years of Italy at CERN, installed in the foyer of the Sinopoli Room of the Auditorium for the duration of the event. The installation is dedicated to the super accelerator of the largest particle physics laboratory in the world, and the role that Italian research has played and still plays in this great scientific enterprise. Meet LHC, with the suggestive large and spectacular backlit images of the four LHC detectors, will provide the public with the chance to see the complexity of the experimental apparatus used by physicists for their research. And will also provide an opportunity to explore, through a series of photographs, the history of CERN in Geneva, full of Nobel laureates and momentous inventions and discoveries, such as the most recent relating to the Higgs boson, placing the emphasis on the important contribution that, thanks to INFN, Italy has provided for the achievement of its success. L’ignoto (The Unknown) is the tenth edition of the Rome Science Festival. The event, to be held at the Parco della Musica Auditorium in Rome, from 22 to 25 January, is presented by Musica per Roma Foundation in collaboration with Codice. Idee per la Cultura.