From particle physics to the Universe, from the infinitely small to the infinitely large: almost 200 senior high school students from Italy and other countries in the world  participated to INSPYRE (International School on modern PhYsics and REsearch), the international school organised by the INFN Frascati National Laboratories, from 4 to 8 April. The international INSPYRE school ended on Friday 8 April with the participation of students from more than 100 school institutes, 79 Italian ones and 22 from different countries in the world: France, Germany, India, Indonesia, Ireland, Lithuania, Luxembourg, Portugal, Czech Republic, Romania, Sweden, and Turkey. Thanks to this experience, the students approached the world of particle physics research, and the discovery of the mysteries of the universe, following a cycle of online lessons, that, as of Monday 11 April have been available on the public channel YouTube of the INFN National Laboratories of Frascati. Having started in 2011 with 20 students who were mainly Italian, INSPYRE, which is now in its XII edition, is a chance for exchange among students and for discovering the world of scientific research.